Updated: 2014-02-28 02:25:28
Summary
Epichloë festucae is a filamentous fungus that forms a mutually beneficial symbiotic association with Lolium perenne. This endophyte synthesizes bioprotective lolitrems (ltm) and ergot alkaloids (eas) in planta but the mechanisms regulating expression of the corresponding sub‐telomeric gene clusters are not known. We show here that the status of histone H3 lysine 9 and lysine 27 trimethylation (H3K9me3/H3K27me3) at these alkaloid gene loci are critical determinants of transcriptional activity. Using ChIP‐qPCR we found that levels of H3K9me3 and H3K27me3 were reduced at these loci in plant infected tissue compared to axenic culture. Deletion of E. festucae genes encoding the H3K9‐ (ClrD) or H3K27‐ (EzhB) methyltransferases led to derepression of ltm and eas gene expression ...
Updated: 2014-02-27 04:00:00
(American Society for Microbiology) A team of French investigators has discovered viruses containing genes for antibiotic resistance in a fossilized fecal sample from 14th century Belgium, long before antibiotics were used in medicine. They publish their findings ahead of print in the journal Applied and Environmental Microbiology. (Source: EurekAlert! - Biology)MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
Updated: 2014-02-26 23:00:00
This article is protected by copyright. All rights reserved. (Source: Clinical Microbiology and Infection)
Updated: 2014-02-26 23:00:00
Conclusions:
The KU70-deficient mutant generated herein was effective in improving gene deletion frequency and allowed shorter homology sequences to be used for gene targeting. It retained the key oleaginous and fast growing features of R. toruloides. The strain should facilitate both fundamental and applied studies in this important yeast, with the approaches taken here likely to be applicable in other species in subphylum Pucciniomycotina. (Source: BMC Microbiology - Latest articles)
Updated: 2014-02-26 23:00:00
Conclusion:
The results indicate a promising potential of using DSF and its structurally related molecules as novel adjuvants to conventional antibiotics for treatment of infectious diseases caused by bacterial pathogens. (Source: BMC Microbiology - Latest articles)
Updated: 2014-02-26 23:00:00
ConclusionsThis recombinant chimeric protein‐based immunodetection approach may eventually provide advantages over PCR formats during onsite investigations of biological emergencies or even during routine testing by laboratories.
Significance and Impact of the StudyThe trivalent recombinant PFE protein could be a novel intervention for possible diagnosis/detection of potential biological agents simultaneously in environmental and clinical samples to reduce the responding time and minimize the impact of the bioattack. (Source: Journal of Applied Microbiology)
Updated: 2014-02-26 23:00:00
Abstract
Vibrio vulnificus and Vibrio parahaemolyticus are Gram‐negative marine bacteria naturally found in estuaries such as the Gulf of Mexico and can be pathogenic to humans. We quantified both of these organisms in fish, oyster, sediment, and water using culture‐independent (quantitative PCR; qPCR) and culture‐dependent (direct plating‐colony hybridization; DP‐CH) techniques during the transition period between winter and spring. We correlated these levels to environmental conditions and to abundance of total bacteria and total vibrio. By qPCR, fish intestine samples had the highest V. vulnificus densities and were 2·7, 3·5, and 4·2 logs greater than oyster, sediment and water samples, respectively. Densities of V. parahaemolyticus in fish samples by qPCR were 1·0, 2·1...
Updated: 2014-02-26 14:48:03
Summary
Plasmodium spp and Toxoplasma gondii are important human and veterinary pathogens. These parasites possess an unusual double membrane structure located directly below the plasma membrane named the inner membrane complex (IMC). First identified in early electron micrograph studies, huge advances in genetic manipulation of the Apicomplexa have allowed the visualisation of a dynamic, highly structured cellular compartment with important roles in maintaining the structure and motility of these parasites. This review summarises recent advances in the field and highlights the changes the IMC undergoes during the complex life cycles of the Apicomplexa. (Source: Cellular Microbiology)
Updated: 2014-02-26 14:47:19
ConclusionsAs a whole, F. mosseae showed greater improvements in the performance of Ph. australis seedlings than R. irregularis. In addition, the potential applications of AM fungi as a ″bio‐accelerator″, ″bio‐fortifier″, and ″bio‐enhancer″ in phyto‐rhizoremediation have been discussed.
Significance and Impact of the StudyThe main findings could preliminarily reveal the mechanisms behind AM fungus‐plant symbioses, and could be referred to when optimizing combined phyto‐rhizoremediation before practical applications take place.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)
Updated: 2014-02-26 13:39:51
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 147-161. (Source: Future Microbiology)MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
Updated: 2014-02-26 13:39:50
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 249-261. (Source: Future Microbiology)
Updated: 2014-02-26 13:39:49
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 235-248. (Source: Future Microbiology)
Updated: 2014-02-26 13:39:47
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 175-188. (Source: Future Microbiology)
Updated: 2014-02-26 13:39:46
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 121-124. (Source: Future Microbiology)MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
Updated: 2014-02-26 13:39:45
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 217-233. (Source: Future Microbiology)
Updated: 2014-02-26 13:39:43
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 125-128. (Source: Future Microbiology)
Updated: 2014-02-26 13:39:41
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 163-173. (Source: Future Microbiology)
Updated: 2014-02-26 13:39:40
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 129-133. (Source: Future Microbiology)
Updated: 2014-02-26 13:39:34
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 135-137. (Source: Future Microbiology)MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
Updated: 2014-02-26 13:39:33
Future Microbiology , February 2014, Vol. 9, No. 2, Pages 189-201. (Source: Future Microbiology)
Updated: 2014-02-26 04:00:00
(American Society for Microbiology) South Africa has been financing domestic rainwater harvesting tanks in informal low-income settlements and rural areas in five of that nation's nine provinces. But pathogens inhabit such harvested rainwater, potentially posing a public health hazard, especially for children and immunocompromised individuals, according to a team from the University of Stellenbosch. The research was published ahead of print in Applied and Environmental Microbiology. (Source: EurekAlert! - Infectious and Emerging Diseases)
Updated: 2014-02-25 23:00:00
Abstract
Toxin–antitoxin (TA) loci are widely spread in bacterial plasmids and chromosomes. Toxins affect important functions of bacterial cells such as translation, replication and cell‐wall synthesis, whereas antitoxins are toxin inhibitors. Participation in formation of the dormant state in bacteria is suggested to be a possible function of toxins. Here we show that overexpression of VapC toxin in Mycobacterium smegmatis results in development of morphologically distinct ovoid cells. The ovoid cells were nonreplicating and revealed a low level of uracil incorporation and respiration that indicated their dormant status. To validate the role of VapBC in dormancy formation, we used a model of dormant, ‘nonculturable' (NC) M. smegmatis cells obtained in potassium‐limited conditions...
Updated: 2014-02-25 23:00:00
This article is protected by copyright. All rights reserved. (Source: FEMS Microbiology Letters)
Updated: 2014-02-25 23:00:00
This article is protected by copyright. All rights reserved. (Source: FEMS Microbiology Letters)MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
Updated: 2014-02-25 23:00:00
This study identifies AipA as an A. phagocytophilum surface protein that is critical for infection, demarcates its invasion domain, and establishes a rationale for targeting multiple invasins to protect against granulocytic anaplasmosis. (Source: Cellular Microbiology)
Updated: 2014-02-25 23:00:00
. Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Microbiology Virology Cellular Microbiology Accepted Articles Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues FIND ARTICLES Early View Accepted Articles GET ACCESS Subscribe Renew FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL News Overview Editorial Board Permissions Advertise Contact SPECIAL FEATURES Faculty of 1000 Parasitology Virtual Special Issue Posters Virology Virtual Special Issue Wiley Job Network Highlights of 2012 Virtual Issue Jobs Research Article You
Updated: 2014-02-25 23:00:00
Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Microbiology Virology Cellular Microbiology Accepted Articles Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues FIND ARTICLES Early View Accepted Articles GET ACCESS Subscribe Renew FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL News Overview Editorial Board Permissions Advertise Contact SPECIAL FEATURES Faculty of 1000 Parasitology Virtual Special Issue Posters Virology Virtual Special Issue Wiley Job Network Highlights of 2012 Virtual Issue Jobs Research Article You
Updated: 2014-02-25 23:00:00
Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Microbiology Virology Cellular Microbiology Accepted Articles Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues FIND ARTICLES Early View Accepted Articles GET ACCESS Subscribe Renew FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL News Overview Editorial Board Permissions Advertise Contact SPECIAL FEATURES Faculty of 1000 Parasitology Virtual Special Issue Posters Virology Virtual Special Issue Wiley Job Network Highlights of 2012 Virtual Issue Jobs Research Article
Updated: 2014-02-25 23:00:00
Summary
Rifampicin resistance, a defining attribute of multidrug‐resistant tuberculosis, is conferred by mutations in the β subunit of RNA polymerase. Sequencing of rifampicin‐resistant (RIF‐R) clinical isolates of Mycobacterium tuberculosis revealed, in addition to RIF‐R mutations, enrichment of potential compensatory mutations around the double‐psi β‐barrel domain of the β′ subunit comprising the catalytic site and the exit tunnel for newly synthesized RNA. Sequential introduction of the resistance allele followed by the compensatory allele in isogenic Mycobacterium smegmatis showed that these mutations respectively caused and compensated a starvation enhanced growth defect by altering RNA polymerase activity. While specific combinations of resistance and compensatory al...
Updated: 2014-02-25 10:30:03
Authors:
PMID: 24554788 [PubMed - in process] (Source: Antimicrobial Agents and Chemotherapy)
Updated: 2014-02-25 04:00:00
(University of Southern California - Health Sciences) A Keck Medicine of USC-led team of microbiologists has identified previously unknown interactions between critical proteins in the human immune response system, uncovering two independent regulatory mechanisms that keep the body's immune response in check. Their findings appear in the February 2014 edition of Cell Host & Microbe, the top peer-reviewed scientific journal that focuses on the study of cell-pathogen interaction. (Source: EurekAlert! - Infectious and Emerging Diseases)
Updated: 2014-02-25 04:00:00
(American Society for Microbiology) The active ingredient in vinegar, acetic acid, can effectively kill mycobacteria, even highly drug-resistant Mycobacterium tuberculosis, an international team of researchers from Venezuela, France, and the US reports in mBio, the online open-access journal of the American Society for Microbiology. (Source: EurekAlert! - Biology)
Updated: 2014-02-24 23:00:00
ConclusionWe show that quantification of the HF183 marker is a useful tool for mapping the spatial distribution and potential sources of human sewage contamination in tropical environments such as Singapore.
Significance and ImpactA major challenge for assessment of water quality in tropical environments is the natural occurrence and nonconservative behaviour of FIB. The HF183 marker has been employed in temperate environments as an alternative indicator for human sewage contamination. Our study supports the use of the HF183 marker as an indicator for human sewage in Singapore and motivates further work to determine HF183 marker levels that correspond to public health risk in tropical environments. (Source: Journal of Applied Microbiology)
Updated: 2014-02-24 23:00:00
, , Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Microbiology Journal of Eukaryotic Microbiology Early View Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues FIND ARTICLES Early View Accepted Articles GET ACCESS Subscribe Renew Membership Information FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL Society Information News Overview Editorial Board Permissions Advertise Contact SPECIAL FEATURES Professional Opportunities Wiley Job Network Jobs Original Article Phylogeny of the Poorly Known Ciliates , Microthoracida ,
Updated: 2014-02-24 23:00:00
The precise understanding of the biology of a living cell requires the identification and quantification of the molecular components necessary to sustain life. One such element is RNA. Two independent high-throughput strategies are available to identify the entire collection of RNA molecules produced by a cell population, which is currently... (Source: Proceedings of the National Academy of Sciences)
Updated: 2014-02-24 23:00:00
Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Molecular Microbiology Molecular Microbiology Accepted Articles Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues FIND ARTICLES Early View Accepted Articles GET ACCESS Subscribe Renew FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL News Overview Editorial Board Permissions Advertise Contact SPECIAL FEATURES 3D Interactive Images Faculty of 1000 Prizes Awarded by Molecular Microbiology Virtual Special Issues Wiley Job Network Molecular Microbiology Meeting Jobs Research
Updated: 2014-02-23 23:00:00
Abstract
Exosomes have recently been classified as the newest family members of ‘bioactive vesicles’ that function to promote intercellular communication. Long ignored and thought to be only a mechanism by which cellular waste is removed, exosomes have garnered a huge amount of interest in recent years as their critical functions in maintaining homeostasis through intercellular communication and also in different types of diseases have been demonstrated. Many groundbreaking studies of exosome functions have been performed in the cancer field and the infectious disease areas of study, revealing the importance and also the fascinating complexity of exosomal packaging, targeting, and functions. Selective packaging of exosomes in response to the type of infection, exosomal modulation of th...
Updated: 2014-02-23 23:00:00
Abstract
The expression of phenotypic drug resistance or drug tolerance serves as a strategy for Mycobacterium tuberculosis to survive in vivo antimicrobial drug treatment; however, the mechanisms are poorly understood. Progress toward a more in depth understanding of in vivo drug tolerance and the discovery of new therapeutic strategies designed specifically to treat drug‐tolerant M. tuberculosis are hampered by the lack of appropriate in vitro assays. A library of 2‐aminoimidazole‐based small molecules combined with the antituberculosis drug isoniazid was screened against M. tuberculosis expressing in vitro drug tolerance as microbial communities attached to an extracellular matrix derived from lysed leukocytes. Based on the ability of nine of ten 2‐aminoimidazole compounds to ...
Updated: 2014-02-23 23:00:00
: , , Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Microbiology Virology Pathogens and Disease Early View Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues Virtual Issues FIND ARTICLES Early View Accepted Articles Most Accessed GET ACCESS Subscribe Renew FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL Society Information Overview Editorial Board Permissions Advertise Contact MiniReview Toxin Antitoxin systems : their role in persistence , biofilm formation , and pathogenicity Yurong Wen , Ester Behiels Bart
Updated: 2014-02-23 23:00:00
In this report, three HspX formulas (native and two recombinant variants) were used as vaccines in the guinea pig model of tuberculosis; none were protective during challenge with WT Mtb. However, recombinant HspX was protective in animals challenged with a strain of Mtb lacking hspX (X4‐19), indicating protection was driven by molecules co‐purifying with HspX or an adjuvant effect of recombinant HspX in this system. Mtb X4‐19 was significantly less virulent than WT Mtb. Quantitative PCR and whole genome sequencing identified several genes (Rv2030c‐Rv2032, Rv1062, Rv1771, Rv1907, and Rv3479) with altered expression that may contribute to loss of virulence. Physiological differences required for the establishment of Mtb infection in different hosts may affect the potential of subuni...
Updated: 2014-02-23 23:00:00
Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Applied Microbiology Letters in Applied Microbiology Early View Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues Virtual Issues FIND ARTICLES Early View Accepted Articles GET ACCESS Subscribe Renew FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL Society Information News Overview Editorial Board Permissions Advertise Contact SPECIAL FEATURES Wiley Job Network Jobs Original Article Biocatalysis with Escherichia coli overexpressing cyclopentanone monooxygenase immobilized
Updated: 2014-02-23 23:00:00
Abstract
The transcriptional regulator BrlR is a member of the MerR family of multidrug transport activators that contributes to the high‐level drug tolerance of Pseudomonas aeruginosa biofilms. While MerR regulators are known to activate both the expression of multidrug efflux pump genes and their own transcription upon inducer‐binding, little is known about BrlR activation. We demonstrate using promoter reporter strains, in vivo and in vitro DNA‐binding assays combined with 5'RACE, that BrlR binds to its own promoter, likely via a MerR‐like palindromic sequence. Unlike known MerR multidrug transport activators, BrlR and brlR expression are not activated by multidrug transporter substrates. Instead, BrlR‐DNA binding was enhanced by the secondary messenger c‐di‐GMP. In additi...
Updated: 2014-02-23 23:00:00
(Source: FEMS Microbiology Letters)
Updated: 2014-02-23 23:00:00
(Source: FEMS Microbiology Letters)
Updated: 2014-02-23 23:00:00
Abstract
Conventional and real‐time PCR assays were developed for sensitive and specific detection of Phytophthora colocasiae, an oomycete pathogen that causes leaf blight and corm rot of taro. A set of three primer pairs was designed from regions of the RAS‐related protein (Ypt1), G protein alpha‐subunit (GPA1) and phospho‐ribosylanthranilate isomerase (TRP1) genes. In conventional PCR, the lower limit of detection was 50 pg DNA, whereas in real‐time PCR, the detection limit was 12.5 fg for the primer based on Ypt1 gene. The cycle threshold values were linearly correlated with the concentration of the target DNA (range of R2 = 0.911–0.999). All the primer sets were successful in detecting P. colocasie from naturally infected leaves and tubers of taro. Phytophthora colocas...
Updated: 2014-02-23 23:00:00
Conclusions:
Described system of vectors is a versatile tool for display of heterologous proteins on the surface of B. subtilis spores. Such recombinant spores can be further used as for example biocatalysts or antigen-carriers in vaccine formulations. The lack of antibiotic resistance genes in the system makes such spores an interesting option for applications in which a possible release to the environment can occur. (Source: Microbial Cell Factories)
Updated: 2014-02-23 17:45:03
. . : Warning The NCBI web site requires JavaScript to function . more . NCBI Skip to main content Skip to navigation Resources All Resources Chemicals Bioassays BioSystems PubChem BioAssay PubChem Compound PubChem Structure Search PubChem Substance All Chemicals Bioassays Resources . DNA RNA BLAST Basic Local Alignment Search Tool BLAST Stand-alone E-Utilities GenBank GenBank : BankIt GenBank : Sequin GenBank : tbl2asn Genome Workbench Influenza Virus Nucleotide Database PopSet Primer-BLAST ProSplign Reference Sequence RefSeq RefSeqGene Sequence Read Archive SRA Splign Trace Archive UniGene UniSTS All DNA RNA Resources . Data Software BLAST Basic Local Alignment Search Tool BLAST Stand-alone Cn3D Conserved Domain Search Service CD Search E-Utilities GenBank : BankIt GenBank : Sequin
Updated: 2014-02-23 14:00:56
ConclusionsB. subtilis ALB629 promotes cacao root growth, besides promoting growth of the aerial part of cacao seedlings. It has antimicrobial properties, producing an antifungal compound.
Significance and Impact of the StudyALB629 presented beneficial characteristics for cacao cultivation, being a good biological control agent candidate. Furthermore, it is a potential source of antifungal compound with potential for commercial exploitation.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)
Updated: 2014-02-22 23:00:00
ConclusionThe ASC production with the DAR procedure using the saturated reactants maximizes both the antimicrobial compounds yields and bactericidal effects of the ASC solutions.
Significance and impact of the studyThis study will contribute to increase the efficiency of ASC treatments for disinfections reducing the effective SC concentrations for industrial use.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)
Updated: 2014-02-21 23:00:00
This article reviews the properties of Brevibacillus spp. as better biological tools with varied applications.
PMID: 24563152 [PubMed - as supplied by publisher] (Source: Antonie van Leeuwenhoek)MedWorm Sponsor Message: Find the best Christmas Sales, Boxing Day Sales and January Sales here.
Updated: 2014-02-21 23:00:00
Authors: Li Y, Chan Y, Fu Y, Zhang R, Chiu JM
PMID: 24563153 [PubMed - as supplied by publisher] (Source: Antonie van Leeuwenhoek)
Updated: 2014-02-21 23:00:00
. : Warning The NCBI web site requires JavaScript to function . more . NCBI Skip to main content Skip to navigation Resources All Resources Chemicals Bioassays BioSystems PubChem BioAssay PubChem Compound PubChem Structure Search PubChem Substance All Chemicals Bioassays Resources . DNA RNA BLAST Basic Local Alignment Search Tool BLAST Stand-alone E-Utilities GenBank GenBank : BankIt GenBank : Sequin GenBank : tbl2asn Genome Workbench Influenza Virus Nucleotide Database PopSet Primer-BLAST ProSplign Reference Sequence RefSeq RefSeqGene Sequence Read Archive SRA Splign Trace Archive UniGene UniSTS All DNA RNA Resources . Data Software BLAST Basic Local Alignment Search Tool BLAST Stand-alone Cn3D Conserved Domain Search Service CD Search E-Utilities GenBank : BankIt GenBank : Sequin GenBank
Updated: 2014-02-21 23:00:00
. . : Warning The NCBI web site requires JavaScript to function . more . NCBI Skip to main content Skip to navigation Resources All Resources Chemicals Bioassays BioSystems PubChem BioAssay PubChem Compound PubChem Structure Search PubChem Substance All Chemicals Bioassays Resources . DNA RNA BLAST Basic Local Alignment Search Tool BLAST Stand-alone E-Utilities GenBank GenBank : BankIt GenBank : Sequin GenBank : tbl2asn Genome Workbench Influenza Virus Nucleotide Database PopSet Primer-BLAST ProSplign Reference Sequence RefSeq RefSeqGene Sequence Read Archive SRA Splign Trace Archive UniGene UniSTS All DNA RNA Resources . Data Software BLAST Basic Local Alignment Search Tool BLAST Stand-alone Cn3D Conserved Domain Search Service CD Search E-Utilities GenBank : BankIt GenBank : Sequin
Updated: 2014-02-21 23:00:00
, , . . : Warning The NCBI web site requires JavaScript to function . more . NCBI Skip to main content Skip to navigation Resources All Resources Chemicals Bioassays BioSystems PubChem BioAssay PubChem Compound PubChem Structure Search PubChem Substance All Chemicals Bioassays Resources . DNA RNA BLAST Basic Local Alignment Search Tool BLAST Stand-alone E-Utilities GenBank GenBank : BankIt GenBank : Sequin GenBank : tbl2asn Genome Workbench Influenza Virus Nucleotide Database PopSet Primer-BLAST ProSplign Reference Sequence RefSeq RefSeqGene Sequence Read Archive SRA Splign Trace Archive UniGene UniSTS All DNA RNA Resources . Data Software BLAST Basic Local Alignment Search Tool BLAST Stand-alone Cn3D Conserved Domain Search Service CD Search E-Utilities GenBank : BankIt GenBank : Sequin
Updated: 2014-02-21 23:00:00
. . : Warning The NCBI web site requires JavaScript to function . more . NCBI Skip to main content Skip to navigation Resources All Resources Chemicals Bioassays BioSystems PubChem BioAssay PubChem Compound PubChem Structure Search PubChem Substance All Chemicals Bioassays Resources . DNA RNA BLAST Basic Local Alignment Search Tool BLAST Stand-alone E-Utilities GenBank GenBank : BankIt GenBank : Sequin GenBank : tbl2asn Genome Workbench Influenza Virus Nucleotide Database PopSet Primer-BLAST ProSplign Reference Sequence RefSeq RefSeqGene Sequence Read Archive SRA Splign Trace Archive UniGene UniSTS All DNA RNA Resources . Data Software BLAST Basic Local Alignment Search Tool BLAST Stand-alone Cn3D Conserved Domain Search Service CD Search E-Utilities GenBank : BankIt GenBank : Sequin
Updated: 2014-02-21 23:00:00
Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Infectious Disease Microbiology Clinical Microbiology and Infection Early View Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues FIND ARTICLES Early View Accepted Articles Most Accessed GET ACCESS Subscribe Renew FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL Society Information News Overview Editorial Board Permissions Advertise Contact SPECIAL FEATURES Editor's Choice Toggle to New Microbes and New Infections Wiley Job Network Jobs Review Why is it so difficult to
Updated: 2014-02-21 23:00:00
Skip to Main Content Log in Register Log In E-Mail Address Password Forgotten Password Remember Me Register Institutional Login Home Microbiology Virology Infectious Disease Microbiology Clinical Microbiology and Infection Early View Abstract JOURNAL TOOLS Get New Content Alerts Get RSS feed Save to My Profile Get Sample Copy Recommend to Your Librarian JOURNAL MENU Journal Home FIND ISSUES Current Issue All Issues FIND ARTICLES Early View Accepted Articles Most Accessed GET ACCESS Subscribe Renew FOR CONTRIBUTORS OnlineOpen Author Guidelines Submit an Article ABOUT THIS JOURNAL Society Information News Overview Editorial Board Permissions Advertise Contact SPECIAL FEATURES Editor's Choice Toggle to New Microbes and New Infections Wiley Job Network Jobs Review The role of vaccination in
Updated: 2014-02-12 05:12:49
This blog mainly discuss about all the latest research happening in field of chemistry covering research from all branches like analytical chemistry, organic chemistry, inorganic chemistry, biochemistry and more
[url=http://worldofchemicals.tumblr.com/]world of chemicals - chemistry news [/url]
Updated: 2014-01-31 19:31:44
Cyanine dyes - Non-sulfonated and Sulfonated cyanines
Lumiprobe.com http://www.lumiprobe.com/tech/cyanine-dyes
Sulfonated and non-sulfonated cyanines exhibit very similar fluorescent properties. However, there are a few differences in labeling protocols that should be noticed. Non-sulfonated cyanines must be dissolved in organic co-solvent (DMF or DMSO) prior to use, and added to a solution of target molecule in aqueous buffers. Recommended volume of co-solvent should be 10% for Cy3, Cy5,...