Microbiology

Thiazolidinedione derivatives as novel agents against Propionibacterium acnes biofilms

Updated: 2013-10-29 12:16:34

ConclusionThe anti‐biofilm effect and the effect on biofilm susceptibility of the thiazolidinedione derived quorum sensing inhibitors was clearly demonstrated. Significance and Impact of the StudyPropionibacterium acnes infections are difficult to treat due to the presence of biofilms at the infection site and the associated resistance towards conventional antimicrobials. Our results indicate these thiazolidinedione derivatives can be promising leads used for the treatment of P. acnes infections and as anti‐acne drugs.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)

Human monoclonal single chain antibodies specific to dengue virus envelope protein

Updated: 2013-10-29 12:16:13

Regulated proteolysis in bacterial development

Updated: 2013-10-29 12:15:40

Enterohepatic bacterial infections dysregulate the FGF15-FGFR4 endocrine axis

Updated: 2013-10-29 03:00:00

Conclusions: Bacterial pathogens of the enterohepatic system can disturb the homeostasis of the FGF15/19-FGFR4 endocrine axis. These results open up a possible link between FGF15/19-FGFR4 disruptions and the metabolic and nutritional disorders observed in infectious diseases. (Source: BMC Microbiology - Latest articles)

Detection and characterization of Bifidobacterium crudilactis and B. mongoliense able to grow during the manufacturing process of French raw milk cheeses

Updated: 2013-10-29 03:00:00

Conclusions: According to the observed characteristics such as survival in adverse conditions and their ability to grow under 12[degree sign]C during the manufacturing process of the cheeses, which has never been described for bifidobacteria and which is a very interesting technological asset, these B. crudilactis and B. mongoliense strains should be further investigated for a potential use in new food or in food supplements. (Source: BMC Microbiology - Latest articles)

Lipooligosaccharide locus class of Campylobacter jejuni: sialylation is not needed for invasive infection

Updated: 2013-10-29 03:00:00

Abstract Campylobacter jejuni is a highly diverse enteropathogen that is commonly detected worldwide. It can sometimes cause bacteraemia, but the bacterial characteristics facilitating bloodstream infection are not known. A total of 73 C. jejuni isolates, consecutively collected from blood‐borne infections during a 10‐year period all over Finland and for which detailed clinical information of the patients were available, were included. We screened the isolates by PCR for the lipooligosaccharide (LOS) locus class and for the presence of the putative virulence genes ceuE, ciaB, fucP, and virB11. The isolates were also tested for γ‐glutamyl transpeptidase production. The results were analysed with respect to the clinical characteristics of the patients, and the multilocus sequence typ...

Nationwide laboratory‐based surveillance of invasive beta‐haemolytic streptococci in Denmark from 2005 to 2011

Updated: 2013-10-29 03:00:00

Abstract The aim of this work was to describe national surveillance of invasive beta‐haemolytic streptococci (BHS) in Denmark and to report overall trends and major findings by groups and types of BHS causing laboratory‐confirmed disease from 2005 to 2011. A total of 3063 BHS isolates were received from 2872 patients. Based on confirmed cases the overall annual incidence increased from 6.2 to 8.9 per 100 000 persons between 2005 and 2011. In 2011 the incidences of group A, B, C and G streptococci were 3.1, 2.3, 0.9 and 2.6 per 100 000 persons, respectively. An increase was observed for all groups of BHS, but in particular for group G in men above 65 years of age. Among group A streptococci (GAS), five T‐types (1, 28,12, 3,13,B3264 and B3264) represented 71% and five emm‐types (1...

Cell surface hydrophobicity: a key component in the degradation of polyethylene succinate by Pseudomonas sp. AKS2

Updated: 2013-10-29 03:00:00

ConclusionThe current study establishes a direct correlation between cell surface hydrophobicity of an organism and its potential to degrade a nonpolar polymer like PES. Significance and Impact of the StudyCell surface hydrophobicity manipulation can be used as an important strategy to increase bioremediation of nonpolar polymer like PES.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

In vitro antidermatophytic activity of Otacanthus azureus (Linden) Ronse essential oil alone and in combination with azoles

Updated: 2013-10-29 03:00:00

ConclusionsThe O. azureus essential oil alone or in combination with azoles is a promising antifungal agent in the treatment of human dermatomycoses caused by filamentous fungi. Significance and Impact of the StudyThere is much interest in the study of essential oils for the discovery of new antimicrobial drugs. This study has highlighted the antidermatophytic activity of the O. azureus EO.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)

Microbial communities and symbionts in the hard tick Haemaphysalis longicornis (Acari: Ixodidae) from north China

Updated: 2013-10-28 03:00:00

Natural Haemaphysalis longicornis harboured complex microbial communities. Three types of symbionts (Coxiella-like, Arsenophonus-like and Rickettsia-like symbionts) coexisted in H. longicornis simultaneously. A novel Coxiella-like agent, with 95.31% similarity to the closest taxon was reported. Image: Free-living Haemaphysalis longicornis. (Source: Parasites and Vectors)

Replication of the Escherichia coli chromosome in RNase HI‐deficient cells: Multiple initiation regions and fork dynamics

Updated: 2013-10-28 03:00:00

Abstract DNA replication in Escherichia coli is normally initiated at a single origin, oriC, dependent on initiation protein DnaA. However, replication can be initiated elsewhere on the chromosome at multiple ectopic oriK sites. Genetic evidence indicates that initiation from oriK depends on RNA‐DNA hybrids (R‐loops), which are normally removed by enzymes such as RNase HI to prevent oriK from misfiring during normal growth. Initiation from oriK sites occurs in RNase HI‐deficient mutants, and possibly in wild‐type cells under certain unusual conditions. Despite previous work, the locations of oriK and their impact on genome stability remain unclear. We combined 2D gel electrophoresis and whole genome approaches to map genome‐wide oriK locations. The DNA copy number profiles of var...

Kinetochore composition and its function; lessons from yeasts

Updated: 2013-10-28 03:00:00

Changes in Clinical and Microbiological Periodontal Profiles Relate to Progression of Carotid Intima-Media Thickness: The Oral Infections and Vascular Disease Epidemiology Study [Epidemiology]

Updated: 2013-10-28 03:00:00

Conclusion Longitudinal improvement in clinical and microbial periodontal status is related to a decreased rate of carotid artery IMT progression at 3-year average follow-up. (Source: JAHA:Journal of the American Heart Association)

A model of laboratory surveillance for neuro‐arbovirosis applied during 2012 in the Emilia‐Romagna region, Italy

Updated: 2013-10-27 03:00:00

Developmental biology of Streptomyces from the perspective of 100 actinobacterial genome sequences

Updated: 2013-10-26 04:00:00

This article is protected by copyright. All rights reserved. (Source: FEMS Microbiology Reviews)MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

Dual gene expression cassette vectors with antibiotic selection markers for engineering in Saccharomyces cerevisiae

Updated: 2013-10-25 04:00:00

Conclusions: These vectors allow manipulations in prototrophic yeast strains with expression of two gene cassettes per plasmid, and will be particularly useful for metabolic engineering applications. The vector set expands the (currently limited) selection of antibiotic marker plasmids available for use in yeast, and in addition makes available dual gene expression cassettes on individual plasmids using antibiotic selection. The resistance gene cassettes are flanked by loxP recognition sites to allow CreA-mediated marker removal and recycling, providing the potential for genomic integration of multiple genes. Guidelines for selection using G418 and phleomycin are provided. (Source: Microbial Cell Factories)

Effect of acclimation medium on cell viability, membrane integrity and ability to consume malic acid in synthetic wine by oenological lactobacillus plantarum strains

Updated: 2013-10-25 04:00:00

Conclusionacclimation of oenological strains in media containing ethanol prior to wine inoculation significantly decreases the membrane damage and improves viability in the harsh wine conditions. The role of membrane integrity is crucial to warrant the degradation of L‐malic acid. Significance and Impact of the StudyThe efficiency of multiparametric flow cytometry in monitoring viability and membrane damage along with the malic acid consumption has a strong impact on winemaking because it represents a useful tool for a quick and highly reliable evaluation of oenological parameters.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)

Examination of Factors for use as Potential Predictors of Human Enteric Pathogen Survival in Soil

Updated: 2013-10-25 04:00:00

ConclusionThis study provided evidence of specific properties that impact inactivation of E. coli O157:H7 and Salmonella in soils at 25°C. Significance and Impact of the StudyIdentification of factors influential in the die‐off of enteric pathogens will assist in developing guidelines for safe intervals between field contamination events and planting or harvesting of fresh‐cut produce crops.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)

Dynamics of Neotyphodium uncinatum and N‐formylloline in Italian ryegrass, and their relation to insect resistance in the field

Updated: 2013-10-25 04:00:00

ConclusionLocalization of N. uncinatum and N‐formylloline were discordant in Italian ryegrass. The N. uncinatum‐infected Italian ryegrass was effective to only insects that prefer to feed on particular plant tissues containing N‐formylloline. Significance and Impact of StudyOur data implies that the relationship between insect habits and the dynamics of alkaloids in plants is important for the effective use of endophyte‐infected crops.This article is protected by copyright. All rights reserved. (Source: Journal of Applied Microbiology)MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

Chemical Inhibition of Bacterial Virulence [Gene Regulation]

Updated: 2013-10-25 04:00:00

Skip to main page content Home Current issue Archive Papers in Press Minireviews Reports Classics Reflections Papers of the Week QUICK SEARCH : Author : Keyword : Year : Vol : Page GO Advanced Search Browse the Archive Advertisement Advertisement Disarming Bacterial Virulence through Chemical Inhibition of the DNA Binding Domain of an AraC-like Transcriptional Activator Protein Ji Yang Dianna M . Hocking Catherine Cheng Con Dogovski Matthew A . Perugini 1 Jessica K . Holien Michael W . Parker 2 Elizabeth L . Hartland 1 Marija Tauschek and Roy M . Robins-Browne 3 From the Department of Microbiology and Immunology , The University of Melbourne , Victoria 3010, Department of Biochemistry , La Trobe University , Victoria 3086, Biota Structural Biology Laboratory and Australian Cancer Research

Determination of Antigenic Determinant of Staphylococcal WTA [Microbiology]

Updated: 2013-10-25 04:00:00

Skip to main page content Home Current issue Archive Papers in Press Minireviews Reports Classics Reflections Papers of the Week QUICK SEARCH : Author : Keyword : Year : Vol : Page GO Advanced Search Browse the Archive Advertisement Advertisement Glycoepitopes of Staphylococcal Wall Teichoic Acid Govern Complement-mediated Opsonophagocytosis via Human Serum Antibody and Mannose-binding Lectin Kenji Kurokawa 1 Dong-Jun Jung Jang-Hyun An Katharina Fuchs Yu-Jin Jeon Na-Hyang Kim Xuehua Li Koichiro Tateishi Ji Ae Park Guoqing Xia Misao Matsushita Kazue Takahashi Hee-Ju Park Andreas Peschel and Bok Luel Lee 2 From the National Research Laboratory of Defense Proteins , College of Pharmacy , Pusan National University , Pusan 609-735, Korea , the Cellular and Molecular Microbiology Section ,

Tabrizicola aquatica gen. nov. sp. nov., a novel alphaproteobacterium isolated from Qurugöl Lake nearby Tabriz city, Iran.

Updated: 2013-10-25 04:00:00

Authors: Tarhriz V, Thiel V, Nematzadeh G, Hejazi MA, Imhoff JF, Hejazi MS Abstract A novel Gram-negative, aerobic, non-motile and rod-shaped bacterium was isolated from Qurugöl Lake near Tabriz city. The bacterium grew chemoorganolheterotrophically and chemolithoautotrophically. However, photo-organoheterotrophic, photo-lithoautotrophic and fermentative growth could not be demonstrated. The presence of photosynthesis genes pufL and pufM was not shown and photosynthesis pigments were not formed. Strain RCRI19(T) grew without NaCl and tolerated up to 3 % NaCl. Growth occurred at pH 6-9 (optimum, pH 7) and 15-55 °C (optimum 40-45 °C). Vitamins were not required for growth. The major fatty acids are C18:1 ω7C, 11-methyl C18:1 ω7C, C18:0 3-OH. The predominant respiratory quinon...

Bacillus xiamenensis sp. nov., isolated from intestinal tract contents of a flathead mullet (Mugil cephalus).

Updated: 2013-10-25 04:00:00

. . . . : Warning The NCBI web site requires JavaScript to function . more . NCBI Skip to main content Skip to navigation Resources All Resources Chemicals Bioassays BioSystems PubChem BioAssay PubChem Compound PubChem Structure Search PubChem Substance All Chemicals Bioassays Resources . DNA RNA BLAST Basic Local Alignment Search Tool BLAST Stand-alone E-Utilities GenBank GenBank : BankIt GenBank : Sequin GenBank : tbl2asn Genome Workbench Influenza Virus Nucleotide Database PopSet Primer-BLAST ProSplign Reference Sequence RefSeq RefSeqGene Sequence Read Archive SRA Splign Trace Archive UniGene UniSTS All DNA RNA Resources . Data Software BLAST Basic Local Alignment Search Tool BLAST Stand-alone Cn3D Conserved Domain Search Service CD Search E-Utilities GenBank : BankIt GenBank : Sequin

Response surface optimization for enhanced production of cellulases with improved functional characteristics by newly isolated Aspergillus niger HN-2.

Updated: 2013-10-25 04:00:00

. . : Warning The NCBI web site requires JavaScript to function . more . NCBI Skip to main content Skip to navigation Resources All Resources Chemicals Bioassays BioSystems PubChem BioAssay PubChem Compound PubChem Structure Search PubChem Substance All Chemicals Bioassays Resources . DNA RNA BLAST Basic Local Alignment Search Tool BLAST Stand-alone E-Utilities GenBank GenBank : BankIt GenBank : Sequin GenBank : tbl2asn Genome Workbench Influenza Virus Nucleotide Database PopSet Primer-BLAST ProSplign Reference Sequence RefSeq RefSeqGene Sequence Read Archive SRA Splign Trace Archive UniGene UniSTS All DNA RNA Resources . Data Software BLAST Basic Local Alignment Search Tool BLAST Stand-alone Cn3D Conserved Domain Search Service CD Search E-Utilities GenBank : BankIt GenBank : Sequin

Salinarubrum litoreum gen. nov., sp. nov.: a new member of the family Halobacteriaceae isolated from Chinese marine solar salterns.

Updated: 2013-10-25 04:00:00

Authors: Cui HL, Qiu XX Abstract Three halophilic archaeal strains, XD46(T), YJ-63-S1 and ZS-1-H, were isolated from three Chinese marine solar salterns. All were observed to have pleomorphic cells that lysed in distilled water, stained Gram-negative and formed red-pigmented colonies. They were found to grow optimally at 37 °C, at pH 7.0 and in the presence of 2.6 M NaCl and 0.05 M Mg(2+). The major polar lipids were identified as those typical for members of the Halobacteriaceae but also included major glycolipids chromatographically identical to sulfated mannosyl glucosyl diether (S-DGD-1), mannosyl glucosyl diether (DGD-1) and two unidentified ones. The 16S rRNA gene sequences of the three strains were 99.8-100 % identical, showing most similarity to sequences of members o...