History of Medicine

Causal inference, probability theory, and graphical insights

Updated: 2013-05-10 04:00:00

This article is a US Government work and is in the public domain in the USA. (Source: Statistics in Medicine)

Emergence of multilateral proto-institutions in global health and new approaches to governance: analysis using path dependency and institutional theory

Updated: 2013-05-10 04:00:00

: Log on BioMed Central Journals Gateways 2.65 Search this journal BioMed Central for Go Advanced search Home Articles Authors Reviewers About this journal My Globalization and Health Globalization and Health Volume 9 Viewing options Abstract Provisional PDF 561KB Associated material PubMed record About this article Readers' comments Related literature Cited by Google blog search Other articles by authors on Google Scholar GÃ³mez EJ Atun R on PubMed GÃ³mez EJ Atun R Related articles pages on Google on Google Scholar on PubMed Tools Download references Email to a friend Order reprints Post a comment Share this article Tweet More options . Citeulike LinkedIn Del.icio.us Email Facebook Google+ Mendeley Twitter Research Emergence of multilateral proto-institutions in global health and new

SkepDoc to Speak in Portland

Updated: 2013-05-07 17:40:59

I’ll be speaking in Portland, Oregon on May 17th. Details here.

Clinical Evaluation and Endoscopic Classification of Bronchomalacia in Dogs

Updated: 2013-05-06 04:00:00

Conclusion and Clinical ImportanceResults of this study provide evidence for 2 different types of bronchial collapse. Endoscopic scoring scheme has proved to be promising in the bronchomalacia classification, although further evaluation of its applicability in larger canine populations is needed. (Source: Journal of Veterinary Internal Medicine)MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

Treatment With Topotecan Plus Cyclophosphamide in Children With First Relapse of Neuroblastoma

Updated: 2013-05-05 15:12:32

ConclusionsTOPO/CTX was well tolerated and resulted in response rates and PFS similar to those reported for patients treated on COG 9462. Our study provides additional toxicity, historical endpoints, and time‐to‐progression data against which new agents and combination therapies using TOPO/CTX as a backbone can be measured. Pediatr Blood Cancer 2013;9999:XX–XX. © 2013 Wiley Periodicals, Inc. (Source: Pediatric Blood and Cancer)

Meta‐analysis of contemporary short‐ and long‐term mortality rates in patients diagnosed with critical leg ischaemia

Updated: 2013-05-03 04:00:00

ConclusionEarly mortality rates in patients diagnosed with CLI have improved slightly compared with previous historical data, but long‐term mortality rates are still high. (Source: British Journal of Surgery)

Standardized Patients: Pearls and Pitfalls, Lessons Learned (Pamela Rockwell DO)

Updated: 2013-05-02 04:00:00

attachment 1: Background/historical information on standardized patients and OSCEs attachment 2: Description/explanation of Pearls and Pitfalls, lessons learned in use of standardized patients (Source: Family Medicine Digital Resources Library (FMDRL) Recently Uploaded)MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.

Outcomes in stage I testicular seminoma: A population‐based study of 9193 patients

Updated: 2013-04-30 04:00:00

CONCLUSIONSModern radiotherapy as applied in this large population‐based study is not associated with excess CVD mortality. Although increased all‐cause mortality exists, cumulative SMN risk is considerably smaller than reported in historical series, but additional follow‐up will be required to characterize long‐term trends. The increased risk of suicide, previously unreported in men with stage I seminoma, requires confirmation. Cancer 2013. © 2013 American Cancer Society. (Source: Cancer)

Designs for randomized phase II clinical trials with two treatment arms

Updated: 2013-04-29 04:00:00

AbstractThe most common primary statistical end point of a phase II clinical trial is the categorization of a patient as either a ‘responder’ or ‘nonresponder’. The primary objective of typical randomized phase II anticancer clinical trials is to evaluate experimental treatments that potentially will increase response rate over a historical baseline and select one to consider for further study. We propose single‐stage and two‐stage designs for randomized phase II clinical trials, precisely defining various type I error rates and powers to achieve this objective. We develop a program to compute these error rates and powers exactly, and we provide many design examples to satisfy pre‐fixed requirements on error rates and powers. Finally, we apply our method to a randomized phase...

[Media Watch] Chagas disease in context

Updated: 2013-04-27 05:18:39

In Chagas Disease: History of a Continent's Scourge, François Delaporte offers a thorough historical account of the discovery of American trypanosomiasis—ie, Chagas disease. He reflects on the scientific methods and politics underlying Carlos Chagas's discovery of Trypanosoma cruzi and the decades of challenge, experimentation, and reinvention that ensued before Chagas disease was ultimately defined. (Source: The Lancet Infectious Diseases)MedWorm Sponsor Message: Find the best Christmas presents and January Sales in the UK with this simple shopping directory.