Hotspots of genetic rearrangement
Updated: 2011-04-06 02:06:22
Scientists have zoomed in on mouse chromosomes to map hotspots of genetic recombination - sites where DNA breaks and reforms to shuffle genes. The findings of the researchers at the National Institutes of Health and Uniformed Services University of Health Sciences (USU) have the potential to improve the detection of genes associated with disease and to help understand the root causes of genetic abnormalities. The research, published online April 3 in Nature, moves researchers one step closer to understanding how mammals evolve and respond to their environments........