The molecules of life 143 Biochemistry 2010-09-02T20:26:33 Science Guy barry.david.adams@gmail.com Bench Marks 2010-09-01T16:11:01

Large segments of DNA can vary in copy number between individuals. Such copy number variations (CNVs) contribute greatly to genetic diversity and are also thought to be associated with susceptibility or resistance to some diseases, including cancer. Simple Copy Number Determination with Reference Query Pyrosequencing (RQPS), featured in the September issue of Cold Spring [...]

67dd3c1ece56092b038933d13ea3f69f biochemistry «WordPress.com Tag Feed 2010-08-31T20:05:48

Jim Maher, Ph.D. Mark McNiven, Ph.D. Dev Mukhopadhyay, Ph.D. _______________________________________

699949304511bb4abcc3218cf3c84dad Cheminfostream 2010-08-31T18:18:59

9fa14dc4472c19a1a5380a3529346e4f biochemistry «WordPress.com Tag Feed 2010-08-28T10:28:11

(ScienceDaily) – Using a 3-D visualization method called X-ray crystallography, Song Tan at Pe

899cc92dd072e32ae2248802b7210a32 CCOM Research News 2010-08-27T19:53:46

Leaders of the Roy J. Carver Charitable Trust of Muscatine, Iowa, University of Iowa Health Care and the UI Foundation have announced a $2 million gift from the Carver Charitable Trust that will establish a core facilities operational endowment for proteomics in the UI Roy J. and Lucille A. Carver College of Medicine. Proteomics involves the [...]

1277e334f58ac550dddf5b032ea0db9c CCOM Research News 2010-08-27T19:47:14

Leaders of the Roy J. Carver Charitable Trust of Muscatine, Iowa, University of Iowa Health Care and the UI Foundation have announced a $2 million gift from the Carver Charitable Trust that will establish the Roy J. Carver Chair in Biochemistry. Charles Brenner, Ph.D., professor and head of biochemistry, will serve as the Roy J. Carver [...]

e5d7b12704548c8f9fa88485069b1daf Bench Marks 2010-08-23T15:56:55

Improvements in automation and acquisition time have made the microscope a viable platform for performing hundreds of concurrent parallel experiments. Using these sorts of tools, it is now possible to run high-throughput screens for protein function and interaction in living cells, examining dynamic cellular processes to distinguish between primary and secondary phenotypes, and to [...]

a5ad6f3293258055f6d1049ae8f82fb2 biochemistry «WordPress.com Tag Feed 2010-08-21T06:42:54

Openings for Guest Lecturers on weekends in IOCB Bangalore . People with expertise in Microbiology,I

461c84abc12b5d590af78f3f94ab20a2 CCOM Research News 2010-08-20T20:42:03

Steven Lentz (right), MD, PhD, Professor, Department of Internal Medicine, has been named the new director of the Medical Scientist Training Program (MSTP) in the UI Carver College of Medicine. Dr. Lentz previously served as the associate director of the program. Pamela Geyer, PhD, Professor of Biochemistry, who directed the program from 1999 to 2006, [...]

6531977cdea8aba075befd8ab4df4c84 biochemistry «WordPress.com Tag Feed 2010-08-19T17:21:51

Masquerade parties are a lot of fun. Inspiration for costumes comes from all kinds of sources. At th

c021697fe4ca0d6a035a1d3597f8a8ee biochemistry «WordPress.com Tag Feed 2010-08-18T00:48:33

Algae Anatomy Biochemistry and Biotechnology DOWNLOAD FULL

53aefd7c2d3b385ec7c39e7fdfefa93b Bench Marks 2010-08-17T18:18:15

Immunoprecipitation is a commonly used technique for isolating and purifying a protein of interest. An antibody for the protein is incubated with a cell extract, and the resulting antibody/antigen complex is pulled out of solution. The method used for preparation of the cell extract can be critical for the experiment’s success. The [...]

a10a7ee53e1845f54a06463b7c4e3edb Microarray and bioinformatics 2010-08-10T11:13:13

Single patient Clinical Trial are not new idea, FDA did not focus since such trial canot prove the efficacy and safety of medicine over a large pool of patient with sufficient data. But I was forced to re-think after reading the article http://www.technologyreview.in/biomedicine/12537/ why cant we use the the concept mentioned in to overcome the [...]

ef721d6dc57904c87df3997a6c6e76af Bench Marks 2010-08-09T19:52:53

Producing recombinant proteins in bacterial hosts is a widely-used laboratory procedure. But generating a large yield of protein is often challenging. Getting enough raw material for experiments can be a time-consuming and frustrating process. In the August issue of Cold Spring Harbor Protocols, Jianjun Wang and colleagues present a method for Preparation [...]

deb30fe2ace79f4130a75b73faa0b560 Bench Marks 2010-08-02T15:55:08

Zinc finger nucleases (ZFNs) are artificial restriction enzymes made by fusing an engineered zinc finger DNA-binding domain to the DNA cleavage domain of a restriction enzyme. ZFNs can be used to generate targeted genomic deletions of large segments of DNA in a wide variety of cell types and organisms. In the August issue [...]

1909051670985c16031d420f5d133301 Bench Marks 2010-07-21T15:52:13

While it is possible to analyze the global lipid composition of a cell, a deeper understanding of what lipids are doing within that cell is more difficult to come by. Though the lipid components may be known, finding their exact position, how dynamically they change location, and how rapidly they are metabolized presents an [...]

a565d15865215b3bb4dbb3f5b6332a24 Bench Marks 2010-07-12T21:53:22

The zebrafish (Danio rerio) has rapidly become a favored model organism for studying developmental biology. One of the most commonly used methods for genetic manipulation in the zebrafish is the delivery of plasmids or oligonucleotides to cells within the living embryo via electroporation. When cells are exposed to brief electrical fields, transient membrane destabilization [...]

a4af6aa4e27175c9e3c61cacd95cbcfc Bench Marks 2010-07-06T21:54:49

Cold Spring Harbor Laboratory Press’ new Drosophila Neurobiology laboratory manual covers the three main approaches taught in the CSHL course: studying neural development, recording and imaging the nervous system, and studying behavior. The featured electrophysiology paper is part of the recording/imaging section, while the second featured article in the July issue of Cold Spring [...]

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